Changes in the pattern of human life in this world especially the food consumption patterns that lead to a "Westernized" tend to contain excess fat and will cause various diseases that are currently known as metabolic syndrome.
One faction / derived from fats that circulate in the body is cholesterol, in addition to the fraction of fat called triglyceride materials and phopholipid. Levels of fat in the blood which increases commonly called hyperlipidemia.
In normal circumstances the body actually does need cholesterol for metabolic processes but in limited quantities. The source material can be derived cholesterol from the diet, but the body is also able to produce it themselves. For example in the liver tissue produces about 1 gram of cholesterol per day.
Consumption of foods containing cholesterol all the fat of animal origin, such as pork, mutton, chicken skin, chicken egg yolks, shrimp, crab, squid, jerohan and type of food ingredients derived from milk such as butter, cheese, and so on. Raw foods mentioned above contain the type of saturated fat, whereas unsaturated fats are typically derived from plant materials, such as corn oil, sesame, and soybean oil.
Excess cholesterol in the blood is called hypercholesterolemia tend to give a negative effect or damage the walls of blood vessels, especially on the walls of arteries throughout the body, including the coronary arteries that provide vascularization to the heart wall.
Excessive cholesterol in the blood vessels will oxidize and having interaction with macrophage cells and other biological substances will form foam cells (foam cells) that will accumulate in the blood vessel wall, and then infiltrated into the artery wall and form a crust or a plaque. Small pockets of the plaque will accumulate through a process called atherosclerosis that prolonged (decades) along with the level of food consumption of saturated fatty acids and less physical activity and not balanced by the amount of fat consumption.
Atherosclerosis, or plaque crust will break and will enter the bloodstream throughout the body and clumps of fat will clog the artery walls of the heart (coronary artery). Inhibition of blood flow to the heart wall resulting in cell death of heart muscle and cause a fatal condition called a wedge and cardiac death or myocardial infarct.
The attack on the heart are usually triggered by the existence of barriers or lack of blood flow by 50% in the coronary arteries due to atherosclerosis is plaque.
Symptoms are easy to recognize the existence of coronary heart attack is chest pain, chest distress and chest pain that spreads to the shoulders, neck, jaw, and arms.
Types of blood are needed to predict the presence of hypercholesterolemia is a "medical check-ups" to predict the incidence of illness in individuals to undetectable levels of cholesterol in the blood and several other parameters that support diagnostics in the scope of the metabolic syndrome (millitus diabetes, obesity, hypertension).
Before determining the type of cholesterol tests, required an understanding of some types of fat and cholesterol species involved and the dominant role in the process of atherosclerosis. Flow / transport of cholesterol material that will circulate throughout the body via a compound called lipoproteins, because as is known sustansi fats can not dissolve in water / liquid blood. There are several components-lipoprotein cholesterol is called Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Very Low Density Lipoprotein (VLDL), and Chylomikron.
Based on research conducted from various experts, concluded the involvement of LDL cholesterol and HDL cholesterol in the process of atherosclerosis is more dominant. Because 60-80% of LDL cholesterol can transport the body to the whole tissue / organ / system, and will be absorbed by the body as a base material for forming the source of metabolic hormones and fat cells.
The need for materials that are transported by LDL cholesterol are limited, so that there is excess will be discharged into the bloodstream and will accumulate in the blood vessel walls, causing inflammation and produce a crust / atherosclerosis plaque above. As is known LDL composition is composed of fat and less protein and is an unstable compound, so the unused cholesterol which will be released and accumulate in the arteries vulnerable.
HDL compounds have higher levels of stability because it has a composition of protein and less fat. Because it is not easy to unravel so on HDL cholesterol are not easily separated and do not easily form a clot, so as to prevent the formation of plaque on blood vessel walls.
Based on the assumptions above, the higher LDL levels than the normal rate will result in atherosclerosis, otherwise if the HDL level lower than normal rate it will increase the risk of heart disease due to atherosclerosis.
